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TVIS30000141
Basic Information
VIS ID
TVIS30000141
Fusion event
HIV-SETDB2 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr13
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
50022002/49447866 (Hg38)
End
50022002/49447866 (Hg38)
Orient
-
Location type
Intronic
Target gene
SETDB2
miRNAs that regulate target gene
hsa-mir-3161
;
hsa-mir-3157-5p
;
hsa-mir-513b-5p
;
hsa-mir-4735-5p
;
hsa-mir-4719
;
hsa-mir-4293
Nearest miRNA
hsa-mir-2276/Upstream/5251666; hsa-mir-1267/Downstream/548549;
Nearest TSS
ENST00000623511/Upstream/3107;
ENST00000317257/Downstream/3686;
Nearest CpG islands
None/Target,
chr13-CpG: 551/Upstream/3264
,
chr13-CpG: 60/Downstream/48020
Upstream sequence
ttcagtatttttgtgtctaagacccagtagtgatttgggccttgagtttttttcttgcatgtcaaggttatacttatctcataaaaaaaagttgagtagc
Downstream sequence
ttcccatatttttcctgcttcagaacagtttgtatatgataaaaattagccgttctctgaaagttttgtacaattcatctgtaaaagtttatggacctag
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
Sample Information
×
Sample name
Patient3
Sample type
PBMC
Age
59
Gender
Male
CpG Island Information
×
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