Basic Information
VIS ID
TVIS30000146
Fusion event
HIV-CCP110 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr16
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
19559834/19548512 (Hg38)
End
19559834/19548512 (Hg38)
Orient
-
Location type
Intronic
Target gene
CCP110
miRNAs that regulate target gene
hsa-mir-129-2-3p ; hsa-mir-193b-3p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-3679-3p ; hsa-mir-6734-3p ; hsa-mir-3667-3p ; hsa-mir-500a-5p ; hsa-mir-129-5p ; hsa-mir-3194-3p ; hsa-mir-3672 ; hsa-mir-431-5p ; hsa-mir-4524a-3p ; hsa-mir-4711-3p ; hsa-mir-5691 ; hsa-mir-6733-3p ; hsa-mir-6805-3p ; hsa-mir-6864-3p ; hsa-mir-8055
Nearest miRNA
hsa-mir-1225/Upstream/1053936; hsa-mir-11401/Downstream/1957537;
Nearest TSS
ENST00000527434/Upstream/780; ENST00000537186/Downstream/6728;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/24199, chr16-CpG: 63/Downstream/6652
Upstream sequence
ATTTGTGCTTTGGACAGTTGATGCAATGTGATTGCTTTCTTTGAATTTTGAACATTTAGACCTTAATGCCAGTGACTTATTAATTTTTTTATATTCAATT
Downstream sequence
AGAACCCCTAAGACATCAGTGAAGGGGGTTGTGCAAAATAGACAGAAGCCTTCACAGAGCAGAGTGCCTAACAGAGTGCCTGTTTCAGGTTTGTAGAAAA
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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