Basic Information
VIS ID
TVIS30000148
Fusion event
HIV-CMAHP integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr6
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
25133307/25133079 (Hg38)
End
25133307/25133079 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
CMAHP
Nearest miRNA
hsa-mir-3691/Upstream/6561199; hsa-mir-10398/Downstream/2014547;
Nearest TSS
ENST00000381078/Upstream/76006; ENST00000461945/Downstream/145999;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/221721, chr6-CpG: 36/Downstream/6613
Upstream sequence
acaaaggaaagaaagaaaaagaaagagagagagagaaaggaaggaaggaagttagttcaagacaaaccagaaagcccaagcatgtcatgaacaatctgta
Downstream sequence
taagtcacaagaagaagatttataaaaaacaaaacaaaacaaaaacttttatatgatcaagttgcctatgattaaagggaaataataatggtctttctag
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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