Basic Information
VIS ID
TVIS30000152
Fusion event
HIV-chr1 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr1
Cytoband
q22
Reference genome
GRCh37/hg19
Start
155081688/155109212 (Hg38)
End
155081688/155109212 (Hg38)
Orient
+
Location type
Inergenic
Nearest miRNA
hsa-mir-101-1/Upstream/133429; hsa-mir-1182/Downstream/85965;
Nearest TSS
ENST00000473358/Upstream/23690; ENST00000497282/Downstream/18248;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/23632, chr1-CpG: 147/Downstream/16746
Nearby gene
EFNA1(+18661) ;
Upstream sequence
catgagccaccgcacccggccTCTCtcttttcttttctttttttcttctttctttCTCATTTTCAAAAGCTGAACACAACAGCTAAACTTACAGATTGCC
Downstream sequence
ACCCCCTTTAACATTCCCACTTAACGAAGCAGCATTTTGGGTGCCTTTGAATTATTCATACGAATCGTGTTCCTTCCATGCTCAGTCTTGTGTTCCATGA
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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