Basic Information
VIS ID
TVIS30000156
Fusion event
HIV-ELF1 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr13
Cytoband
q14.11
Reference genome
GRCh37/hg19
Start
41552107/40977971 (Hg38)
End
41552107/40977971 (Hg38)
Orient
+
Location type
Intronic
Target gene
ELF1
miRNAs that regulate target gene
hsa-mir-194-5p
Nearest miRNA
hsa-mir-2276/Upstream/167110; hsa-mir-1267/Downstream/123048;
Nearest TSS
ENST00000623511/Upstream/184813; ENST00000379487/Downstream/4254;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/55301, chr13-CpG: 160/Downstream/82065
Upstream sequence
taggaagttcaaaactgaagcctgtacacatggtaatttagtattaacaaaggtggcagtttaagtgtgaaaaacataaaacattcaataaatggtgaag
Downstream sequence
ggctaacaccactatttgtgggagtgggggaagaatcttcaaatcatgaatacctcacatcatacaaaaataaactgcagatggactgaggagccaaaca
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
Curate