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TVIS30000160
Basic Information
VIS ID
TVIS30000160
Fusion event
HIV-GATAD2B integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr1
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
153872754/153900278 (Hg38)
End
153872754/153900278 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1F
Target gene
GATAD2B
miRNAs that regulate target gene
hsa-mir-590-3p
;
hsa-mir-181a-5p
;
hsa-mir-32-5p
;
hsa-mir-30a-5p
;
hsa-mir-744-5p
;
hsa-mir-505-5p
;
hsa-mir-221-5p
;
hsa-mir-766-3p
;
hsa-mir-193b-3p
;
hsa-mir-484
;
hsa-mir-331-3p
;
hsa-mir-365a-3p
;
hsa-mir-186-5p
;
hsa-mir-221-3p
;
hsa-let-7c-5p
;
hsa-mir-1260b
;
hsa-mir-25-3p
;
hsa-mir-92a-3p
;
hsa-mir-363-3p
;
hsa-mir-367-3p
;
hsa-mir-338-5p
;
hsa-mir-92b-3p
;
hsa-mir-19a-3p
;
hsa-mir-19b-3p
;
hsa-mir-1199-5p
;
hsa-mir-6751-3p
;
hsa-mir-4760-3p
;
hsa-mir-6832-3p
;
hsa-mir-642a-5p
;
hsa-mir-3120-3p
;
hsa-mir-4469
;
hsa-mir-6892-3p
;
hsa-mir-335-3p
;
hsa-mir-2276-5p
;
hsa-mir-4468
;
hsa-mir-3915
;
hsa-mir-1255b-5p
;
hsa-mir-1255a
;
hsa-mir-6797-5p
;
hsa-mir-1249-5p
;
hsa-mir-765
;
hsa-mir-4533
;
hsa-mir-7-5p
;
hsa-mir-3928-3p
;
hsa-mir-6876-5p
;
hsa-mir-4779
;
hsa-mir-4476
;
hsa-mir-6891-5p
;
hsa-mir-3173-3p
;
hsa-mir-6824-5p
;
hsa-mir-8059
;
hsa-mir-4471
;
hsa-mir-6823-3p
;
hsa-mir-2114-3p
;
hsa-mir-29a-5p
;
hsa-mir-4293
;
hsa-mir-6783-5p
;
hsa-mir-6792-3p
;
hsa-mir-6075
;
hsa-mir-3162-3p
;
hsa-mir-6865-3p
;
hsa-mir-30e-3p
;
hsa-mir-30d-3p
;
hsa-mir-30a-3p
;
hsa-mir-329-5p
;
hsa-mir-4801
;
hsa-mir-4731-3p
;
hsa-mir-513b-5p
;
hsa-mir-3119
;
hsa-mir-6069
;
hsa-mir-7151-5p
;
hsa-mir-3158-3p
;
hsa-mir-4446-3p
;
hsa-mir-5088-5p
;
hsa-mir-589-3p
;
hsa-mir-4713-5p
;
hsa-mir-1260a
;
hsa-mir-2116-3p
;
hsa-mir-532-3p
;
hsa-mir-150-5p
;
hsa-mir-6887-3p
;
hsa-mir-1224-3p
;
hsa-mir-1255b-2-3p
Nearest miRNA
hsa-mir-101-1/Upstream/210485; hsa-mir-1182/Downstream/62073;
Nearest TSS
ENST00000473358/Upstream/1327;
ENST00000641267/Downstream/21752;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/116419
,
chr1-CpG: 48/Downstream/22083
Upstream sequence
aggccgaggcaggcggatcacgaggtcaggaattcgagacaaatctggccaatatggtgaaaccccatctctacttaaaaaaatacaaaaattagctgga
Downstream sequence
cgtggtggcacgcacctgtaatcccagctactcaggaggcttgaggcaggagaatcacttgaaccagggaggcggaggttacagtgagccgagatcatgc
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
Sample Information
×
Sample name
Patient3
Sample type
PBMC
Age
59
Gender
Male
CpG Island Information
×
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