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TVIS30000162
Basic Information
VIS ID
TVIS30000162
Fusion event
HIV-SGPL1 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr10
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
72582687/70822931 (Hg38)
End
72582687/70822931 (Hg38)
Orient
-
Location type
Intronic
Target gene
SGPL1
miRNAs that regulate target gene
hsa-mir-125b-5p
;
hsa-mir-155-5p
;
hsa-mir-124-3p
;
hsa-mir-7-5p
;
hsa-mir-1226-3p
;
hsa-mir-27a-3p
;
hsa-mir-199a-3p
;
hsa-mir-199b-3p
;
hsa-mir-216a-3p
;
hsa-mir-222-5p
;
hsa-mir-27b-3p
;
hsa-mir-128-3p
;
hsa-mir-936
;
hsa-mir-1204
;
hsa-mir-3129-5p
;
hsa-mir-3147
;
hsa-mir-3681-3p
;
hsa-mir-4425
;
hsa-mir-4435
;
hsa-mir-8086
;
hsa-mir-139-5p
;
hsa-mir-204-5p
;
hsa-mir-211-5p
;
hsa-mir-548v
;
hsa-mir-4796-3p
;
hsa-mir-3609
;
hsa-mir-548ah-5p
;
hsa-mir-345-3p
;
hsa-mir-3148
;
hsa-mir-125a-5p
;
hsa-mir-670-5p
;
hsa-mir-1289
;
hsa-mir-2110
;
hsa-mir-2114-5p
;
hsa-mir-4319
;
hsa-mir-4324
;
hsa-mir-4271
;
hsa-mir-4433a-3p
;
hsa-mir-4459
;
hsa-mir-4725-3p
;
hsa-mir-4768-3p
;
hsa-mir-1273f
;
hsa-mir-6716-5p
;
hsa-mir-6780b-5p
;
hsa-mir-218-5p
;
hsa-mir-101-3p
;
hsa-mir-6832-3p
;
hsa-mir-144-3p
;
hsa-mir-93-5p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
;
hsa-mir-20a-5p
;
hsa-mir-17-5p
;
hsa-mir-106b-5p
;
hsa-mir-106a-5p
;
hsa-mir-7158-5p
;
hsa-mir-4711-3p
;
hsa-mir-4708-5p
;
hsa-mir-6088
;
hsa-mir-4770
;
hsa-mir-143-3p
;
hsa-mir-4732-3p
;
hsa-mir-506-5p
;
hsa-mir-892c-5p
;
hsa-mir-1268b
;
hsa-mir-6741-5p
;
hsa-mir-1268a
;
hsa-mir-7977
;
hsa-mir-6748-5p
;
hsa-mir-876-3p
;
hsa-mir-323a-5p
;
hsa-mir-6769b-5p
;
hsa-mir-6769a-5p
;
hsa-mir-92a-2-5p
;
hsa-mir-654-5p
;
hsa-mir-541-3p
;
hsa-mir-8485
;
hsa-mir-4789-3p
;
hsa-mir-3064-3p
;
hsa-mir-4640-5p
;
hsa-mir-4726-5p
;
hsa-mir-24-3p
;
hsa-mir-4284
;
hsa-mir-564
;
hsa-mir-4755-3p
;
hsa-mir-4524a-3p
;
hsa-mir-4673
;
hsa-mir-4645-5p
;
hsa-mir-3918
;
hsa-mir-6715b-5p
;
hsa-mir-4269
;
hsa-mir-6895-5p
;
hsa-mir-3622a-5p
;
hsa-mir-4524b-3p
;
hsa-mir-548s
;
hsa-mir-3926
;
hsa-mir-767-5p
;
hsa-mir-873-5p
;
hsa-mir-5002-5p
;
hsa-mir-7153-3p
;
hsa-mir-125b-1-3p
Nearest miRNA
hsa-mir-1265/Upstream/3419521; hsa-mir-107/Downstream/967816;
Nearest TSS
ENST00000439456/Upstream/6961;
ENST00000409118/Downstream/21566;
Nearest CpG islands
None/Target,
chr10-CpG: 68/Upstream/6385
,
chr10-CpG: 55/Downstream/64963
Upstream sequence
GCTTTTATTGCCTCTATTGGTAATATGACAGGGACTGTAAGAAACACAATTGAACTTACAGAGATATGCAGATGATATTCACTAAAGATAATCTTCATCT
Downstream sequence
CAAGTATTTTTTATATGTGGGCACTTCTAATTTTATACATTTTTCTATTTAAAAAGCATTACATTTTAAAATTTGTACCTGTTTTGACATTTGGCAAAAA
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
Sample Information
×
Sample name
Patient3
Sample type
PBMC
Age
59
Gender
Male
CpG Island Information
×
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