Basic Information
VIS ID
TVIS30000168
Fusion event
HIV-RAB14 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr9
Cytoband
q33.2
Reference genome
GRCh37/hg19
Start
123957655/121195377 (Hg38)
End
123957655/121195377 (Hg38)
Orient
+
Location type
Intronic
Target gene
RAB14
miRNAs that regulate target gene
hsa-mir-451a ; hsa-mir-151a-5p ; hsa-mir-155-5p ; hsa-mir-30a-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-544a ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-4662b ; hsa-mir-4647 ; hsa-mir-4426 ; hsa-mir-454-3p ; hsa-mir-3666 ; hsa-mir-130a-3p ; hsa-mir-130b-3p ; hsa-mir-301a-3p ; hsa-mir-4295 ; hsa-mir-301b-3p ; hsa-mir-148a-3p ; hsa-mir-148b-3p ; hsa-mir-152-3p ; hsa-mir-487b-5p ; hsa-mir-487a-5p ; hsa-mir-513a-5p ; hsa-mir-409-5p ; hsa-mir-548ax ; hsa-mir-548ao-5p ; hsa-mir-95-5p ; hsa-mir-2115-3p ; hsa-mir-4703-5p ; hsa-mir-3942-5p ; hsa-mir-181c-3p ; hsa-mir-3120-3p ; hsa-mir-3529-3p ; hsa-mir-27a-3p ; hsa-mir-27b-3p ; hsa-mir-4446-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-623 ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-6832-3p ; hsa-mir-204-5p ; hsa-mir-211-5p ; hsa-mir-548at-5p ; hsa-mir-320a ; hsa-mir-27b-5p
Nearest miRNA
hsa-let-7a-1/Upstream/950327; hsa-mir-12126/Downstream/924705;
Nearest TSS
ENST00000422679/Upstream/36791; ENST00000434663/Downstream/6492;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/120070, chr9-CpG: 121/Downstream/5712
Upstream sequence
TCTTTCCCCATTCAAACCTGGGTAAAAGTAATCACTTAGTCACCTTCAAATTACTGTCTCTTCTGTGCTCTTCTCCCTTGATTTTCCTAATTTCTTTCCC
Downstream sequence
TCTTCTAACTAAAGGTTGTAGCTGTACATACTTTGCTCCTTCTATTTTATGTTAAAGCTATGACTTCTAACAATCCCAAATTTCTACTTCAAATGCTTTA
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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