Basic Information
VIS ID
TVIS30000178
Fusion event
HIV-PDE6G integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
79626816/81659786 (Hg38)
End
79626816/81659786 (Hg38)
Orient
-
Location type
Inergenic
Target gene
PDE6G
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-10226/Upstream/208598; hsa-mir-4525/Downstream/33971;
Nearest TSS
ENST00000595228/Upstream/2727; ENST00000574200/Downstream/3318;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/11257, chr17-CpG: 108/Downstream/6440
Nearby gene
PDE6G(-3209) ;
Upstream sequence
TAATGCAAAACACAGTCACTTGCAGAACCGGTTCTGATGACTTAAATACCAGGTACAATTTTAGCCCTCTACGTAATTGCTTGGAAGTTACTTATGTTTA
Downstream sequence
CATGAAATGAAACTATTAggccgggcacattggctcacgtctgtaatcccagaactttgggaggccaaggtgggcggatcacctgaggtcaggagttgga
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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