Basic Information
VIS ID
TVIS30000180
Fusion event
HIV-EFR3A integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr8
Cytoband
q24.22
Reference genome
GRCh37/hg19
Start
132960557/131948310 (Hg38)
End
132960557/131948310 (Hg38)
Orient
-
Location type
Intronic
Target gene
EFR3A
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-19a-3p ; hsa-mir-19b-3p
Nearest miRNA
hsa-mir-1204/Upstream/1939857; hsa-mir-10400/Downstream/1098171;
Nearest TSS
ENST00000518652/Upstream/8409; ENST00000519920/Downstream/35829;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/43497, chr8-CpG: 18/Downstream/181008
Upstream sequence
ggattccagagtctgactaccccagttttgaactacgcctgtaccgctttctagctgtataccttgagcaagttatttattctctccttgcctcggtttt
Downstream sequence
tcatctgtgaaatgaggagaatgagaataccaatctcacaggattgttgtgtgacatgagttgatatatatgatgctcttggaagagtgcatggcacTGT
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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