Basic Information
VIS ID
TVIS30000181
Fusion event
HIV-CEPT1 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr1
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
111697748/111155126 (Hg38)
End
111697748/111155126 (Hg38)
Orient
+
Location type
Intronic
Target gene
CEPT1
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-23b-3p ; hsa-mir-183-5p ; hsa-mir-26a-5p ; hsa-mir-670-3p ; hsa-mir-580-3p ; hsa-mir-6770-5p ; hsa-mir-4797-3p ; hsa-mir-1253 ; hsa-mir-545-5p ; hsa-mir-100-3p ; hsa-mir-186-5p ; hsa-mir-3133
Nearest miRNA
hsa-mir-101-1/Upstream/1556159; hsa-mir-11399/Downstream/1306644;
Nearest TSS
ENST00000473358/Upstream/7449; ENST00000483427/Downstream/18012;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/14445, chr1-CpG: 91/Downstream/48565
Upstream sequence
ccagtattttggaatagtttcagaagaattggtgtagttctttaaaagtttggtagaattcagcagtaaaggcatttggtcctgggtttttctttgttgg
Downstream sequence
aaaactttttaatatttattcaatcttgttatttgttattagtctgttaaggttttctatttcttttggttcaatctttataggttatacgtgtctaaaa
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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