Basic Information
VIS ID
TVIS30000183
Fusion event
HIV-LINC00824 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr8
Cytoband
q24.21
Reference genome
GRCh37/hg19
Start
129440797/128428551 (Hg38)
End
129440797/128428551 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
LINC00824
Nearest miRNA
hsa-mir-1204/Upstream/278363; hsa-mir-10400/Downstream/1055506;
Nearest TSS
ENST00000518652/Upstream/332032; ENST00000519048/Downstream/537450;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/578573, chr8-CpG: 122/Downstream/1510575
Upstream sequence
AAACAACTGCCATGACTAGGCAGAGTGAGAAAGTCTCAtttgtaatctgccttcctgccttctcatcttgcagctactattcatttttgagctggaagac
Downstream sequence
tttacctcaagcaagagttttgactccctgccttaagcctttgtttctgcatctgtaaattgatgactatgattgcttaactcacaagatagttggggga
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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