Basic Information
VIS ID
TVIS30000184
Fusion event
HIV-ACOT7 integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr1
Cytoband
p36.31
Reference genome
GRCh37/hg19
Start
6366195/6306135 (Hg38)
End
6366195/6306135 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
ACOT7
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-1229-3p ; hsa-mir-18a-3p ; hsa-mir-324-3p
Nearest miRNA
hsa-mir-12136/Upstream/443394; hsa-mir-101-1/Downstream/123699;
Nearest TSS
ENST00000473358/Upstream/10631; ENST00000607670/Downstream/46114;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/24783, chr1-CpG: 135/Downstream/86824
Upstream sequence
aaaaccagtcaggcgtggcggcgcgcgcctgcaatcgcaggcactcggcaggctgaggcaggagaatcaggcagggaggttgcagtgagccaagatggca
Downstream sequence
gcagcacagtccagcttcggctcggcatcagagggagaccgtggcaagagagggagagggagaccgtggggagagggggagggggagggggagagggaga
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
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