Basic Information
VIS ID
TVIS30000189
Fusion event
HIV-DRAM2 integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr1
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
111671520/111128898 (Hg38)
End
111671520/111128898 (Hg38)
Orient
-
Location type
Intronic
Target gene
DRAM2
miRNAs that regulate target gene
hsa-mir-4668-5p ; hsa-mir-548c-3p ; hsa-mir-125b-5p
Nearest miRNA
hsa-mir-101-1/Upstream/1529931; hsa-mir-11399/Downstream/1332872;
Nearest TSS
ENST00000473358/Upstream/871; ENST00000480324/Downstream/10622;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/164513, chr1-CpG: 95/Downstream/10707
Upstream sequence
gaatatagggggctggctgTATTAAAAGTTTTTCAAAACGAAAGCAGACAAGTTCTCAGATGGAGAAAAAAAATACTGTGAAAGACCCTCATGAATCTTA
Downstream sequence
AATATGTACCTTCCGGAGTTACTAAAGAATGGTGTGGCTCCTTAGGCTACATATTCCACTAGCAGAGTGGTAATTATTTATCAAATTATTTCTCGAATTG
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
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