Basic Information
VIS ID
TVIS30000190
Fusion event
HIV-IFI16 integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr1
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
158983016/159013226 (Hg38)
End
158983016/159013226 (Hg38)
Orient
+
Location type
Intronic
Target gene
IFI16
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-98-5p ; hsa-mir-26b-5p ; hsa-mir-136-5p ; hsa-mir-3684
Nearest miRNA
hsa-mir-101-1/Upstream/2076982; hsa-mir-1182/Downstream/886753;
Nearest TSS
ENST00000473358/Upstream/3216; ENST00000567661/Downstream/1455;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/831513, chr1-CpG: 44/Downstream/158186
Nearest cancer related gene
IFI16(TSG, No orient, 0)
Upstream sequence
agtccaaggatcctcatgttctCGTAAGAAGGAAGCttttttttttttttttttttttttttgacggagtctcactctgtcacccaggctggagtgtagt
Downstream sequence
ggcacgatctccgctcactgcaacctccgtctcctgggttcaagcaattctcctgcctcagcctcccgagtagctgggactgcaagcgcttgccaccaca
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
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