Basic Information
VIS ID
TVIS30000193
Fusion event
HIV-USP47 integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr11
Cytoband
p15.3
Reference genome
GRCh37/hg19
Start
11868131/11846584 (Hg38)
End
11868131/11846584 (Hg38)
Orient
+
Location type
Intronic
Target gene
USP47
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-34a-5p ; hsa-mir-21-5p ; hsa-mir-204-5p ; hsa-mir-218-5p ; hsa-let-7a-5p ; hsa-let-7b-5p ; hsa-let-7c-5p ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-202-3p ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-mir-4711-5p ; hsa-mir-7112-3p ; hsa-mir-8066 ; hsa-mir-98-5p
Nearest miRNA
hsa-mir-210/Upstream/63362; hsa-let-7a-2/Downstream/317099;
Nearest TSS
ENST00000527297/Upstream/4518; ENST00000525367/Downstream/33602;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/4113, chr11-CpG: 94/Downstream/161606
Upstream sequence
GAAAAAGAGTAGAAATGTAAATTCTTTATCTCTGGGTTTTTTTCTCCTGTCTTTCATGCAATCACTACTTCTGTCTGGAACTGGTTTTGGCATCTAATGA
Downstream sequence
TGATGATGATagtaataaccagtatttattgagcatttatttatataccagatactgttggttgtgctttgtattaactcatttgagcttcacagcaacc
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
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