Basic Information
VIS ID
TVIS30000194
Fusion event
HIV-A2ML1 integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr12
Cytoband
p13.31
Reference genome
GRCh37/hg19
Start
9003092/8850496 (Hg38)
End
9003092/8850496 (Hg38)
Orient
-
Location type
Intronic
Target gene
A2ML1
miRNAs that regulate target gene
hsa-mir-1304-5p ; hsa-mir-6765-5p ; hsa-mir-6087 ; hsa-mir-3197 ; hsa-mir-4772-3p ; hsa-mir-3925-3p ; hsa-mir-199b-5p ; hsa-mir-199a-5p ; hsa-mir-1825 ; hsa-mir-1306-5p ; hsa-mir-1304-3p ; hsa-mir-6890-3p ; hsa-mir-6787-3p ; hsa-mir-6736-3p ; hsa-mir-216a-5p ; hsa-mir-891a-3p ; hsa-mir-5693
Nearest miRNA
hsa-mir-141/Upstream/1886305; hsa-let-7i/Downstream/388971;
Nearest TSS
ENST00000382841/Upstream/5213; ENST00000545850/Downstream/6739;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/151689, chr12-CpG: 56/Downstream/63854
Upstream sequence
caacataatgagcttctgtctctacaaaagaaattaaaaaaatagccagatggtagttgtgtcctacttggaaggctgaggtggaaggatcacttgagtc
Downstream sequence
tgggaggtggaggctgcagtgaagcaagatcacattgcttcactcctgcttgggtgacagagcaaaacccttctcaaaaTCAACAACGACAACGACAACA
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
Curate