Basic Information
VIS ID
TVIS30000195
Fusion event
HIV-MUC8 integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr12
Cytoband
q24.33
Reference genome
GRCh37/hg19
Start
133052957/132476371 (Hg38)
End
133052957/132476371 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA12E
Target gene
MUC8
Nearest miRNA
hsa-let-7i/Upstream/4182193; hsa-mir-6763/Downstream/105626;
Nearest TSS
ENST00000382841/Upstream/14129; ENST00000542061/Downstream/13180;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/54, chr12-CpG: 29/Downstream/3812
Nearby gene
FBRSL1(+57666) ;
Upstream sequence
CAGGCCGGTCATCACGGGCGGTCGTCACTCTCAAAGCCGCTCTCCGGGGCCTTTTCCTCcctgatcgcctcttcgtattgtgtcacccatgggactggat
Downstream sequence
cagggtccaccccaacaacctcgctttaccttgacaccctcattaaagacccctttatgcagtcacatcctgaggtcgtgggggtgggacttcagcatgt
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
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