Basic Information
VIS ID
TVIS30000197
Fusion event
HIV-STK24 integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr13
Cytoband
q32.2
Reference genome
GRCh37/hg19
Start
99211921/98559667 (Hg38)
End
99211921/98559667 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA13D
Target gene
STK24
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-1-3p ; hsa-mir-877-3p ; hsa-mir-186-5p ; hsa-mir-218-5p ; hsa-mir-578 ; hsa-mir-29b-2-5p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-3925-3p ; hsa-mir-766-3p ; hsa-mir-140-5p
Nearest miRNA
hsa-mir-1297/Upstream/351067; hsa-mir-1267/Downstream/796464;
Nearest TSS
ENST00000623511/Upstream/37669; ENST00000434547/Downstream/16537;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/84577, chr13-CpG: 180/Downstream/16423
Upstream sequence
TCCTAGTTTTTGTCATGCGATTAAATGGCCACAAAGTCTACACTTACGTACCATTTTTCGTAAAATAGCAAAGATCTTTACAACAAAGCCTGACAACACT
Downstream sequence
CCCTCTTTTTCTTAAAGTGTACTTCTATCCAAATAGTTTCCATTTCTCACAAAAGTTAAATCACTAAAGACAACCAATCATACCAAAACAAAAATTTGAA
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
Curate