Basic Information
VIS ID
TVIS30000208
Fusion event
HIV-RHBDF2 integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr17
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
74476016/76479934 (Hg38)
End
74476016/76479934 (Hg38)
Orient
+
Location type
Exonic
Target gene
RHBDF2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-7-5p ; hsa-mir-98-5p ; hsa-mir-615-3p ; hsa-let-7a-5p ; hsa-let-7b-5p ; hsa-let-7c-5p ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-2467-3p ; hsa-mir-3125 ; hsa-mir-3150b-3p ; hsa-mir-3179 ; hsa-mir-3202 ; hsa-mir-3622b-5p ; hsa-mir-3916 ; hsa-mir-4253 ; hsa-mir-4257 ; hsa-mir-4266 ; hsa-mir-4436b-3p ; hsa-mir-4458 ; hsa-mir-4476 ; hsa-mir-4500 ; hsa-mir-4632-5p ; hsa-mir-4688 ; hsa-mir-4695-5p ; hsa-mir-4779 ; hsa-mir-4784 ; hsa-mir-583 ; hsa-mir-6735-5p ; hsa-mir-6743-5p ; hsa-mir-6859-5p ; hsa-mir-6862-5p ; hsa-mir-6876-5p ; hsa-mir-6879-5p ; hsa-mir-765 ; hsa-mir-7843-5p
Nearest miRNA
hsa-mir-10226/Upstream/381858; hsa-mir-1250/Downstream/256516;
Nearest TSS
ENST00000595228/Upstream/2203; ENST00000590555/Downstream/1593;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/7860, chr17-CpG: 60/Downstream/20976
Upstream sequence
AAGTAGGCTGGGTTCTTCCTCTTGGGGAGGAAGGAGGGAGGGCAGGCGGTGGTGTGTGCAGCCCAGGTCCTGGGCTGGCTTTTCTTTAGCCTCCTATTCT
Downstream sequence
GAAAACCCTGAGAACAAACTTCAACCCTGATTTATGCCCCAATTTGCTTTCATTTGGAAatatatatatataatgtgtgtgtgtgtgtgtgtgtgtgtgt
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
Curate