Basic Information
VIS ID
TVIS30000210
Fusion event
HIV-GNG7 integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
2522787/2522789 (Hg38)
End
2522787/2522789 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
GNG7
miRNAs that regulate target gene
hsa-mir-92a-3p ; hsa-mir-3925-5p ; hsa-mir-4311 ; hsa-mir-4524a-3p
Nearest miRNA
hsa-mir-1227/Upstream/87789; hsa-let-7e/Downstream/107926;
Nearest TSS
ENST00000633603/Upstream/46433; ENST00000592525/Downstream/109165;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/9091, chr19-CpG: 46/Downstream/1941
Upstream sequence
tgcagtgagcagagatcacgccactgcactccagcctgggggacagagtgagactctgtctcaaaaaaaaaaaaaaaaaaaaaaaaaaaagaAGGAAAGG
Downstream sequence
ACCATCCATGCATACCACACCGCAGGGGAATCTCCAGGGCCTGGGATGTGTAgcatgcttctgtttgtgtaatgtgtttaagaggactttttttagacag
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
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