Basic Information
VIS ID
TVIS30000211
Fusion event
HIV-SAFB integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
5628436/5628425 (Hg38)
End
5628436/5628425 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
SAFB
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-1229-3p ; hsa-mir-331-5p ; hsa-mir-92a-3p ; hsa-let-7c-5p ; hsa-let-7b-5p
Nearest miRNA
hsa-mir-1227/Upstream/695685; hsa-let-7e/Downstream/761213;
Nearest TSS
ENST00000633603/Upstream/4379; ENST00000590485/Downstream/13426;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/4724, chr19-CpG: 100/Downstream/51997
Nearest cancer related gene
SAFB(TSG, No orient, 0)
Upstream sequence
aaatgcttgggaccagaagggtttcattttttggattttgtgcggtattttcgtacgcataatgagataatcttgggattggggcccaaatctaaacaag
Downstream sequence
aaatttgtttcttatacacctgaagataatttaataccatattttttataattttgtgcatgaaacaaaactttcactaattccacacatcaggtgtgga
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
Curate