Basic Information
VIS ID
TVIS30000212
Fusion event
HIV-PBX4 integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr19
Cytoband
p13.11
Reference genome
GRCh37/hg19
Start
19676184/19565375 (Hg38)
End
19676184/19565375 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
PBX4
miRNAs that regulate target gene
hsa-mir-1274a
Nearest miRNA
hsa-mir-10395/Upstream/130217; hsa-let-7e/Downstream/833897;
Nearest TSS
ENST00000633603/Upstream/1551; ENST00000559614/Downstream/14579;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/19366, chr19-CpG: 60/Downstream/52943
Upstream sequence
ACATGGGTTGAGGACACCCTGGAGCTGGCGTGTCTTAGAACTCTGCTGCCTAAAACTGGATGTTGCTGGAACCTGAACCTGGGAAGGGGCTGGAAGGAAA
Downstream sequence
ACAAGACTGTCTGAGGTGGGCCGGGAGGGACAGCGCCTCTGGCTGCCATGCAGCAGGCGGCAGGTTACGTTCCGTGTTCTCTTCAGGAAAAGTGAGAGCC
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
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