Basic Information
VIS ID
TVIS30000215
Fusion event
HIV-USP39 integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr2
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
85864772/85637649 (Hg38)
End
85864772/85637649 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2L
Target gene
USP39
miRNAs that regulate target gene
hsa-mir-193b-3p
Nearest miRNA
hsa-mir-1285-2/Upstream/5771066; hsa-mir-10b/Downstream/145951;
Nearest TSS
ENST00000437798/Upstream/1563; ENST00000481409/Downstream/1644;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/21095, chr2-CpG: 174/Downstream/115727
Upstream sequence
ACAAAGCACCTGCCTAGTGGCAGCTCTGCCTGGTCCCTGTCATACTAGTGCACTTTTTCAGTTTGGGAGTTAGTGGTTGGATGTACTGTGCTGGTTTAAG
Downstream sequence
TGTTCTGGCCACTAGGTGGTGCTGCTGTGTTTTTTCAGAAAGCTCAGCTAAGCtttctttttgtttttcttagtctccctctgtcgccaaggctggagtt
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
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