Basic Information
VIS ID
TVIS30000218
Fusion event
HIV-SLC4A7 integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr3
Cytoband
p24.1
Reference genome
GRCh37/hg19
Start
27457140/27415649 (Hg38)
End
27457140/27415649 (Hg38)
Orient
-
Location type
Intronic
Target gene
SLC4A7
miRNAs that regulate target gene
hsa-mir-30a-5p ; hsa-mir-34a-5p ; hsa-mir-19b-3p ; hsa-mir-25-3p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-30b-5p ; hsa-mir-519d-3p ; hsa-mir-93-5p ; hsa-mir-20b-5p ; hsa-mir-17-5p
Nearest miRNA
hsa-mir-12127/Upstream/1750710; hsa-let-7g/Downstream/3746055;
Nearest TSS
ENST00000440867/Upstream/14605; ENST00000607601/Downstream/8437;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/46074, chr3-CpG: 132/Downstream/67794
Upstream sequence
taaaaacccgttcaggggattttcttaacaggatctgatctgggaactcatctgctgcctcctggatggcagaagctgcttctccagttattttgacatt
Downstream sequence
ttttaagccaaacttctttctaaaattaccaaacaatctttgctggcactaaattatccgatccttcgcttttcttttgctttatgttgtcgtaaaatga
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
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