Basic Information
VIS ID
TVIS30000226
Fusion event
HIV-HIVEP1 integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr6
Cytoband
p24.1
Reference genome
GRCh37/hg19
Start
12076908/12076675 (Hg38)
End
12076908/12076675 (Hg38)
Orient
-
Location type
Intronic
Target gene
HIVEP1
miRNAs that regulate target gene
hsa-mir-221-3p ; hsa-mir-98-5p ; hsa-mir-32-5p ; hsa-mir-23a-3p ; hsa-mir-363-3p ; hsa-mir-25-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-433-3p ; hsa-mir-92b-3p ; hsa-mir-1206 ; hsa-mir-7154-5p ; hsa-mir-595 ; hsa-mir-410-3p ; hsa-mir-3613-3p ; hsa-mir-190a-3p ; hsa-mir-3163 ; hsa-mir-548e-5p
Nearest miRNA
hsa-mir-3691/Upstream/1636881; hsa-mir-10398/Downstream/4064881;
Nearest TSS
ENST00000381078/Upstream/61088; ENST00000399469/Downstream/49071;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/63841, chr6-CpG: 44/Downstream/672970
Nearest cancer related gene
HIVEP1(TSG, No orient, 0)
Upstream sequence
gaaggacaaaccctgtgtcctcacatggctgaagagcggaagagagtaaacccactcctgcagtccttttttatatcagcataggtccatcatgagggtg
Downstream sequence
gagccttcatgacctaaacaccgcccagtagaccctgcctcccattgctgttgcattgtggattaagtttccaacacatgcattttggaggggacaaaaa
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
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