Basic Information
VIS ID
TVIS30000231
Fusion event
HIV-STK3 integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr8
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
99548720/98536492 (Hg38)
End
99548720/98536492 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA8B
Target gene
STK3
miRNAs that regulate target gene
hsa-mir-141-3p ; hsa-mir-9-5p ; hsa-mir-128-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-133b
Nearest miRNA
hsa-mir-12123/Upstream/142754; hsa-mir-10400/Downstream/1000144;
Nearest TSS
ENST00000518652/Upstream/9566; ENST00000517397/Downstream/11670;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/108295, chr8-CpG: 90/Downstream/288741
Upstream sequence
caataagctatgggctatgatcacaaacaccatattccagtctagatgacagagtgagacccttctcttaaaaaaaaatcaagtaaggttttctaggaaa
Downstream sequence
gttctgttttcttgatataggcacaatcctttctgttttttgctcttttctactgcctggaatacagacttgatggctagagatcctacatttactctgc
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
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