Basic Information
VIS ID
TVIS30000240
Fusion event
HIV-NXF1 integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr11
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
62565646/62798174 (Hg38)
End
62565646/62798174 (Hg38)
Orient
+
Location type
Intronic
Target gene
NXF1
miRNAs that regulate target gene
hsa-mir-615-3p ; hsa-mir-487b-3p
Nearest miRNA
hsa-mir-129-2/Upstream/5403; hsa-let-7a-2/Downstream/1543675;
Nearest TSS
ENST00000527297/Upstream/1116; ENST00000535867/Downstream/432;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/6091, chr11-CpG: 68/Downstream/6917
Upstream sequence
gtgagtcaagattgcaccactgcactctgggtaacagagcaagactccatccaaaaaaaaaaaaaaaaaGggcctggtgcgagtggctcacgtctgtaat
Downstream sequence
cccagcactttgggaggccgaggtaggtggatcacctgaggtcaggaattcaaggccagcctggcgaacatggtgaaaccctgtctctactaaaaataca
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
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