Basic Information
VIS ID
TVIS30000241
Fusion event
HIV-chr12 integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr12
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
84994877/84601098 (Hg38)
End
84994877/84601098 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA12B
Nearest miRNA
hsa-let-7i/Upstream/3442637; hsa-mir-1178/Downstream/2143970;
Nearest TSS
ENST00000382841/Upstream/316707; ENST00000393212/Downstream/266735;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/1913231, chr12-CpG: 17/Downstream/310323
Nearby gene
SLC6A15(-55117) ;
Upstream sequence
GACTTGTTTAATTTTCTATTTTTGTTTCTTTTATGTTTATACAGTAAATAGTAAATAAGCTACACAACCTAAATGTGCTCTAGAAATAAATTATTCCTCT
Downstream sequence
TTACAATTAAATAGCATAAAAACGAGTGGGTATTTTCTAATATTTTATTAAAAATAAGCCAAATACATTTATATTAGTCAGCTAAAAGGATAAAGTTACT
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
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