Basic Information
VIS ID
TVIS30000265
Fusion event
HIV-AIP integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr11
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
67244337/67476866 (Hg38)
End
67244337/67476866 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
AIP
miRNAs that regulate target gene
hsa-mir-6887-5p ; hsa-mir-6795-5p ; hsa-mir-6870-5p ; hsa-mir-7111-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-6825-5p ; hsa-mir-1268b ; hsa-mir-1268a ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-6797-5p ; hsa-mir-7106-5p ; hsa-mir-1249-5p ; hsa-mir-765 ; hsa-mir-711 ; hsa-mir-3195 ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-4738-5p ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-4779 ; hsa-mir-1321 ; hsa-mir-6853-5p ; hsa-mir-34a-5p ; hsa-mir-3945 ; hsa-mir-4253 ; hsa-mir-6862-5p
Nearest miRNA
hsa-mir-10392/Upstream/431158; hsa-let-7a-2/Downstream/13379;
Nearest TSS
ENST00000527297/Upstream/7594; ENST00000529797/Downstream/6175;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/7384, chr11-CpG: 46/Downstream/6007
Nearby gene
RPL32P1(+9049) ;
Nearest cancer related gene
AIP(TSG, No orient, 0)
Upstream sequence
gggattgtaaacgcaccaatcagcaccctgtcaaaacggaccaatcagctctctggaaaatggatcaattggctctctgtaaagtggcccaatcagcagg
Downstream sequence
atgtgggtggggctagataagagaataaaagcaggctgcccgagctatcggtggcaactggctcgggttgttttgcacactgtggaagctttattctttt
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
Curate