Basic Information
VIS ID
TVIS30000271
Fusion event
HIV-LTA4H integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr12
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
96418506/96024728 (Hg38)
End
96418506/96024728 (Hg38)
Orient
+
Location type
Intronic
Target gene
LTA4H
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-26b-5p ; hsa-mir-125b-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p
Nearest miRNA
hsa-let-7i/Upstream/714744; hsa-mir-1178/Downstream/1467181;
Nearest TSS
ENST00000382841/Upstream/9554; ENST00000547346/Downstream/595;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/28831, chr12-CpG: 41/Downstream/10508
Upstream sequence
TTCTTAGACATTAAAATAAAAACAGTCCTCATTTCTTGGGAttttttttttttttttgagacggagtttcactcttgttgcccaggctggagttcaatgg
Downstream sequence
catgatcttggctcactgcaacctccacctcccgggttcaagcaattctcctgcctcaacctcccgagtagctgggattacaggcatgtaccaccacgcc
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
Curate