Basic Information
VIS ID
TVIS30000272
Fusion event
HIV-WSCD2 integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr12
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
108631408/108237631 (Hg38)
End
108631408/108237631 (Hg38)
Orient
-
Location type
Intronic
Target gene
WSCD2
miRNAs that regulate target gene
hsa-mir-4496 ; hsa-mir-4704-5p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-6818-3p ; hsa-mir-6873-3p ; hsa-mir-539-3p ; hsa-mir-485-3p ; hsa-mir-3941 ; hsa-mir-6755-3p ; hsa-mir-593-3p ; hsa-mir-6895-3p ; hsa-mir-570-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-758-3p ; hsa-mir-3611 ; hsa-mir-367-5p ; hsa-mir-1267
Nearest miRNA
hsa-let-7i/Upstream/3645915; hsa-mir-1178/Downstream/398179;
Nearest TSS
ENST00000382841/Upstream/10641; ENST00000552758/Downstream/80286;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/107935, chr12-CpG: 66/Downstream/277294
Upstream sequence
GCATCCATGATTCCCTTGCAGTTACCTAGACAGGCCCTCTTTAGAAGACAATTGAGCAACTATCTGTTGTTCCTCAGGCAAACCTATTCTATGTGCCTTC
Downstream sequence
TCAAAAGTTCCTTTCCAGACATAGTACTCTTCCCTCTCTGGGAGACATTCTGCTAAATGGAATTTTCTCTACATTTGCAGTACTCCTATAGATAAACTCC
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
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