Basic Information
VIS ID
TVIS30000284
Fusion event
HIV-LPIN2 integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr18
Cytoband
p11.31
Reference genome
GRCh37/hg19
Start
2935358/2935360 (Hg38)
End
2935358/2935360 (Hg38)
Orient
+
Location type
Intronic
Target gene
LPIN2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-769-5p
Nearest miRNA
hsa-mir-8078/Upstream/2823021; hsa-mir-1-2/Downstream/949993;
Nearest TSS
ENST00000575820/Upstream/14394; ENST00000581488/Downstream/12878;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/22051, chr18-CpG: 105/Downstream/77189
Upstream sequence
accttattttacttccttaaaagtggcaatgagatgattcaaaattacacatgtgattcatattccatttctagtggacagTAAGTTCTAGAGCTAACTC
Downstream sequence
CCAGTTAAGAAAATATAGGAATGTCACCTTCAAAAAAACAATCAGACAAATCCAGAACGTGAGAGAGCCTAGAAGACACTGGCTGAGCTCTTTAAAAGGT
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
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