Basic Information
VIS ID
TVIS30000291
Fusion event
HIV-TRIM39 integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr6
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
30304759/30336982 (Hg38)
End
30304759/30336982 (Hg38)
Orient
+
Location type
Intronic
Target gene
TRIM39
miRNAs that regulate target gene
hsa-mir-218-5p ; hsa-mir-6866-5p ; hsa-mir-1827 ; hsa-mir-4742-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6515-3p ; hsa-mir-4469 ; hsa-mir-877-3p ; hsa-mir-5193 ; hsa-mir-4667-3p ; hsa-mir-1470
Nearest miRNA
hsa-mir-3143/Upstream/3189294; hsa-mir-10398/Downstream/247350;
Nearest TSS
ENST00000381078/Upstream/7453; ENST00000466327/Downstream/8149;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/9688, chr6-CpG: 36/Downstream/8078
Upstream sequence
tcactatttatagcagctttatgaaatacatttattaagacttgaaagtccaaattacttcttgatccatgggctgccgattggatgttgtgttagcgga
Downstream sequence
cgtgaaaacaacatgaatctcattttacatctctatcagaacttttgggtgatcaagtgcattgtcagtgagcagtaatattttgaaaggaatctttttt
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
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