Basic Information
VIS ID
TVIS30000308
Fusion event
HIV-MPP7 integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr10
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
28552155/28263226 (Hg38)
End
28552155/28263226 (Hg38)
Orient
-
Location type
Intronic
Target gene
MPP7
miRNAs that regulate target gene
hsa-mir-32-5p
Nearest miRNA
hsa-mir-1265/Upstream/3987445; hsa-mir-107/Downstream/26032;
Nearest TSS
ENST00000439456/Upstream/24489; ENST00000634334/Downstream/16916;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/264098, chr10-CpG: 69/Downstream/39248
Upstream sequence
TGTCTAAGTACCTGACCACATATAAATCAGAGGCAATAATAAAATATTTTAAAGAAAACCCAAATTTCTCTGGTGGTAGTGTATTCAAATTGCTTTCATC
Downstream sequence
TAAATACGCTGAGTGAAAGGGCCACTACCATCTGGTAGCAGCCAATCTTGAATTTAAGAAATGAGGAATGTGACCTGATGGGCCTGGGGAGGGTAAAGTC
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
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