Basic Information
VIS ID
TVIS30000314
Fusion event
HIV-LRP5 integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr11
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
68177921/68410453 (Hg38)
End
68177921/68410453 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA11H ; FRA11A
Target gene
LRP5
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-23a-3p ; hsa-mir-375
Nearest miRNA
hsa-mir-10392/Upstream/365496; hsa-let-7a-2/Downstream/672723;
Nearest TSS
ENST00000527297/Upstream/424; ENST00000533695/Downstream/28140;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/19556, chr11-CpG: 20/Downstream/997
Upstream sequence
tgctggctgctttcacctgggccgtctcaccgaagtgtccatggagcctgcgtagggtgggtatctgtgtcgattttacagatgcagaaacaggctcaga
Downstream sequence
gaaaccgagtgacttccctaaggtcacatacccagttagagcagagctgggccaggaagtgctgtctcaggctcctgaccaggtctccttgctttgcact
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
Curate