Basic Information
VIS ID
TVIS30000317
Fusion event
HIV-chr12 integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr12
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
12446196/12293262 (Hg38)
End
12446196/12293262 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1244-3/Upstream/181226; hsa-let-7i/Downstream/471387;
Nearest TSS
ENST00000382841/Upstream/26250; ENST00000543990/Downstream/45412;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/25655, chr12-CpG: 61/Downstream/56746
Nearby gene
LRP6(-4040) ;
Upstream sequence
GTGGTGGTGATTTTTGTTGCATTTGGGAGTTGCTATGAAAGTTGAGGGACTAATTTTTTTTTTCTTTTTGCTTAGGCAAACTCCTGAAAACTACTTCTCT
Downstream sequence
TCCTATTTTCATGCAGAGAAACTTAATTTCTCCTTGCCTTTTCTCCCCCTGTGGAGTTAAAAATAGTATGGATGCATTTATTTTGTGTCAATTTCCATTA
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
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