Basic Information
VIS ID
TVIS30000326
Fusion event
HIV-DIP2B integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr12
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
50964321/50570538 (Hg38)
End
50964321/50570538 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA12A
Target gene
DIP2B
Nearest miRNA
hsa-mir-1244-3/Upstream/336326; hsa-let-7i/Downstream/2328351;
Nearest TSS
ENST00000382841/Upstream/65431; ENST00000546719/Downstream/70267;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/65157, chr12-CpG: 139/Downstream/193177
Upstream sequence
agtggcccatacctgtaatctcagcactttgggaggctgaggcaggcggatcacttgcggtcaggagttcaagaccagcctgaccaacatggtaaaaccc
Downstream sequence
tgtctctattaaaaatgcaaaattagccaggtgtggtggcacatgcctgtaatcccagctacttggaaggctgaggcgagagaatcacttgaatccggga
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
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