Basic Information
VIS ID
TVIS30000327
Fusion event
HIV-C12orf56 integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr12
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
64671065/64277285 (Hg38)
End
64671065/64277285 (Hg38)
Orient
-
Location type
Intronic
Target gene
C12orf56
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-let-7i/Upstream/453558; hsa-mir-1178/Downstream/345224;
Nearest TSS
ENST00000382841/Upstream/6712; ENST00000540203/Downstream/8792;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/54679, chr12-CpG: 73/Downstream/112945
Upstream sequence
ATATTTCTAATGTCTTGGTACAACCTTAGAAAAACAAGTAACTCTTGCTGAGAATTTATACTGTTCATATAAGTAGGAAAATGGTAAAGTATAAGAGTTA
Downstream sequence
ACCCTAAAATCTCTAAGACAGTGATTTTTCACCCATTAGACCCCTGCTATGGAATTACATATACATCATGTTTTGTACACAGACAGACATAAACAGATTT
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
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