Basic Information
VIS ID
TVIS30000340
Fusion event
HIV-XPO6 integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr16
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
28164266/28152945 (Hg38)
End
28164266/28152945 (Hg38)
Orient
+
Location type
Intronic
Target gene
XPO6
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-122-5p ; hsa-mir-324-5p ; hsa-mir-320a ; hsa-mir-185-5p ; hsa-mir-222-3p ; hsa-mir-181b-5p ; hsa-mir-16-5p ; hsa-mir-4260 ; hsa-mir-1227-5p ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-6816-5p ; hsa-mir-3196 ; hsa-mir-3180-3p ; hsa-mir-6825-5p ; hsa-mir-3180 ; hsa-mir-6787-5p ; hsa-mir-663a ; hsa-mir-1908-5p ; hsa-mir-3188 ; hsa-mir-1273e ; hsa-mir-7847-3p ; hsa-mir-885-3p ; hsa-mir-31-5p ; hsa-mir-6894-5p ; hsa-mir-765 ; hsa-mir-7154-3p ; hsa-mir-766-5p ; hsa-mir-6820-5p ; hsa-mir-2467-3p ; hsa-mir-1827 ; hsa-mir-4692 ; hsa-mir-4514 ; hsa-mir-4657 ; hsa-mir-4491 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-576-3p
Nearest miRNA
hsa-mir-1225/Upstream/2127635; hsa-mir-11401/Downstream/238037;
Nearest TSS
ENST00000527434/Upstream/27; ENST00000635780/Downstream/264;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/88970, chr16-CpG: 100/Downstream/58255
Upstream sequence
TTCAATCCAAAGTTCTTTCAGTACAGAACTATACAAATTTGTAATATATTTTCTTTTAAAAATATAAAGGCCTGCAACAATTACCTACAGGACAGGCAAC
Downstream sequence
CCTTCATTCCATTAACCACCTGAAACATAGCAGAAAAGCAACTTTAATCCTCAGACACTGTCTGCTAAGGCTTCTTATAATCTAGTGCGCTCACATTTTC
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
Curate