Basic Information
VIS ID
TVIS30000365
Fusion event
HIV-DSTN integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr20
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
17582833/17602188 (Hg38)
End
17582833/17602188 (Hg38)
Orient
-
Location type
Intronic
Target gene
DSTN
miRNAs that regulate target gene
hsa-mir-484 ; hsa-mir-380-3p ; hsa-mir-655-5p ; hsa-mir-2054 ; hsa-mir-7162-3p ; hsa-mir-6809-3p ; hsa-mir-4753-3p ; hsa-mir-23c ; hsa-mir-23b-3p ; hsa-mir-23a-3p ; hsa-mir-130a-5p ; hsa-mir-4693-5p ; hsa-mir-6754-3p ; hsa-mir-6837-3p ; hsa-mir-412-3p ; hsa-mir-1236-3p ; hsa-mir-6515-3p ; hsa-mir-4717-3p ; hsa-mir-942-3p ; hsa-mir-5571-5p ; hsa-mir-452-5p ; hsa-mir-4676-3p ; hsa-mir-892c-3p ; hsa-mir-8077 ; hsa-mir-7160-5p ; hsa-mir-4663 ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-4728-3p
Nearest miRNA
hsa-mir-103a-2/Upstream/6952493; hsa-mir-1-1/Downstream/868427;
Nearest TSS
ENST00000382410/Upstream/32098; ENST00000427254/Downstream/17629;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/31516, chr20-CpG: 16/Downstream/12438
Upstream sequence
TTAAAAAGGAAGATAACTCGAGGTCACACCTCACTTGTATttcagtaagcttttactgcacttgattaaaccaagttgctgtgaggaatgcaaatatgag
Downstream sequence
gtcagggtgcacgtattcaggcagcttagagtccattgaagctggtacataagactgaaaattaacaaggatttgaatgaaggtgcatttactgaacttt
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
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