Basic Information
VIS ID
TVIS30000368
Fusion event
HIV-STT3B integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr3
Cytoband
p23
Reference genome
GRCh37/hg19
Start
31576132/31534640 (Hg38)
End
31576132/31534640 (Hg38)
Orient
+
Location type
Intronic
Target gene
STT3B
miRNAs that regulate target gene
hsa-mir-15b-5p ; hsa-mir-23a-3p ; hsa-mir-16-5p
Nearest miRNA
hsa-mir-12127/Upstream/372853; hsa-let-7g/Downstream/971643;
Nearest TSS
ENST00000440867/Upstream/1015; ENST00000436236/Downstream/62166;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/850, chr3-CpG: 104/Downstream/445837
Upstream sequence
AGATTCAAAGAGAGAGAGTCTTTTTTGAGAGTTACTAACTATATAGATAATAAGTGTTCGGGTGGAGGGGGGCAGTAACTTACCTGTATAGTAATATACC
Downstream sequence
AGATTTAAGTTCTGCATTATGGAGAGAAAAATTGGTACTGCAACATCTATTGAACACCAGAGGGGCCCACTCATGGACAATTCAATTTAGATCAGTTAAT
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
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