Basic Information
VIS ID
TVIS30000369
Fusion event
HIV-CTNNB1 integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr3
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
41241710/41200219 (Hg38)
End
41241710/41200219 (Hg38)
Orient
-
Location type
Intronic
Target gene
CTNNB1
miRNAs that regulate target gene
hsa-mir-200a-3p ; hsa-mir-155-5p ; hsa-mir-1826 ; hsa-mir-214-3p ; hsa-mir-124-3p ; hsa-mir-221-3p ; hsa-mir-34a-5p ; hsa-mir-30a-5p ; hsa-mir-1226-3p ; hsa-mir-744-5p ; hsa-mir-532-3p ; hsa-mir-331-3p ; hsa-mir-512-5p ; hsa-mir-624-3p ; hsa-mir-34a-3p ; hsa-mir-34b-5p ; hsa-mir-34c-3p ; hsa-mir-183-3p ; hsa-mir-3591-5p ; hsa-mir-4765 ; hsa-mir-5586-3p ; hsa-mir-8062 ; hsa-mir-4255 ; hsa-mir-548l ; hsa-mir-7849-3p ; hsa-mir-142-3p ; hsa-mir-5010-3p ; hsa-mir-2113 ; hsa-mir-607 ; hsa-mir-4474-3p ; hsa-mir-7108-5p ; hsa-mir-3144-3p ; hsa-mir-891a-3p ; hsa-mir-3688-5p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-3973 ; hsa-mir-875-5p ; hsa-mir-370-3p ; hsa-mir-375 ; hsa-mir-3162-3p ; hsa-mir-150-3p ; hsa-mir-181a-5p ; hsa-mir-320a ; hsa-mir-200a-5p ; hsa-mir-506-5p ; hsa-mir-101-3p ; hsa-mir-885-5p
Nearest miRNA
hsa-mir-12127/Upstream/2061953; hsa-let-7g/Downstream/2913993;
Nearest TSS
ENST00000440867/Upstream/76; ENST00000644395/Downstream/20332;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/79, chr3-CpG: 17/Downstream/690898
Nearest cancer related gene
CTNNB1(OG, No orient, 0)
Upstream sequence
TCGGGCGCTGAGGCAGAGACGCCACCCTAAGTCCCATCAGTCCTGGGGATCGGACCAGTGGACTTTCTCTTAAGATTTCCTCTTTCATTCTTAAGAATAG
Downstream sequence
AAGTGTTATTATTTTTTTTAATGCCCTGGCTATGTGAGTTTGAATCGAAGCAACTTTAAACCTTAGAGCAACTAAACTCTAAGTGCAGCGGGTGCGATGC
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
Curate