Basic Information
VIS ID
TVIS30000380
Fusion event
HIV-ARSB integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr5
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
78264609/78968786 (Hg38)
End
78264609/78968786 (Hg38)
Orient
+
Location type
Intronic
Target gene
ARSB
miRNAs that regulate target gene
hsa-mir-122-5p ; hsa-mir-941 ; hsa-mir-224-5p ; hsa-mir-6874-5p ; hsa-mir-7850-5p ; hsa-mir-505-5p ; hsa-mir-383-3p ; hsa-mir-320e ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-4684-5p ; hsa-mir-769-5p ; hsa-mir-4786-5p ; hsa-mir-3190-5p ; hsa-mir-454-5p ; hsa-mir-6849-3p ; hsa-mir-3675-3p ; hsa-mir-652-5p
Nearest miRNA
hsa-mir-10397/Upstream/6090123; hsa-mir-103a-1/Downstream/3871369;
Nearest TSS
ENST00000502646/Upstream/13412; ENST00000523472/Downstream/16463;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/319389, chr5-CpG: 116/Downstream/15708
Upstream sequence
AAAATAAAAAATCAATCCATATCCCTTTTTGGTAATAAGGGTCTCTGAGAGTACAGCGGTCTCCAACGTGGATAGTAAACTCTTGCAAGGCCCTAAGGTG
Downstream sequence
GCATTTAGAACTCCAACAAAGGTAATGGGTTTGCCCACCATAAGGTCAGCACAGAGCCCTGTTTACAGAGGTAACATTAGAAAGCAGCCCCATTACAGTG
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
Curate