Basic Information
VIS ID
TVIS30000382
Fusion event
HIV-PDLIM7 integration
Validated
No
Detection method
NG-SGS
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30024859
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr5
Cytoband
q35.3
Reference genome
GRCh37/hg19
Start
176911513/177484512 (Hg38)
End
176911513/177484512 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA5G
Target gene
PDLIM7
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-124-3p ; hsa-mir-30a-5p ; hsa-mir-24-3p ; hsa-mir-132-3p ; hsa-mir-17-5p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-10397/Upstream/855012; hsa-mir-1229/Downstream/2313766;
Nearest TSS
ENST00000502646/Upstream/39; ENST00000506025/Downstream/502;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/10877, chr5-CpG: 87/Downstream/7061
Upstream sequence
ctcaccccaaacctctcctcccacagccatccccatcacgcggatggcaactccattctcctgtctgctgcagccaaacacaccctcctctcacacccca
Downstream sequence
caccaggtccaccaggaaatccagtggggcccacccccaaggcacatccagattctgagtgcttctcacagcctccctgaagtgaggtaagccatggcca
Reference
Sharaf, R., et al.HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest,2018,128(9): 4074-4085.
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