Basic Information
VIS ID
TVIS30000395
Fusion event
HIV-TP73 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr1
Cytoband
p36.32
Reference genome
GRCh37/hg19
Start
3576231/3659667 (Hg38)
End
3576231/3659667 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
TP73
miRNAs that regulate target gene
hsa-mir-193a-5p ; hsa-mir-205-5p ; hsa-mir-4668-5p ; hsa-mir-3613-3p ; hsa-mir-7114-3p ; hsa-mir-1180-5p ; hsa-mir-4750-3p ; hsa-mir-548at-5p ; hsa-mir-4429 ; hsa-mir-320d ; hsa-mir-320c ; hsa-mir-320b ; hsa-mir-320a ; hsa-mir-34a-5p
Nearest miRNA
hsa-mir-12136/Upstream/98877; hsa-mir-101-1/Downstream/2203005;
Nearest TSS
ENST00000473358/Upstream/6906; ENST00000604194/Downstream/9105;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/6595, chr1-CpG: 40/Downstream/30865
Nearest cancer related gene
TP73(OG, No orient, 0)
Upstream sequence
cgttaaacaggacaagaatctaatatggggcgcacaatatggctttctactgaaatatatgttctttctacatcacccctctttctactaaaaataatct
Downstream sequence
cagtaagattattattattattattatttttgagacagagttccactccgtcgctcaaggctagagtgtagtggcatcatctcgactcactgcaaactct
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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