Basic Information
VIS ID
TVIS30000398
Fusion event
HIV-UBXN11 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr1
Cytoband
p36.11
Reference genome
GRCh37/hg19
Start
26623286/26296795 (Hg38)
End
26623286/26296795 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
UBXN11
miRNAs that regulate target gene
hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-513a-5p ; hsa-mir-324-5p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-5088-3p ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-4286 ; hsa-mir-1273g-3p ; hsa-mir-6807-3p ; hsa-mir-217
Nearest miRNA
hsa-mir-12136/Upstream/390341; hsa-mir-101-1/Downstream/257747;
Nearest TSS
ENST00000473358/Upstream/16673; ENST00000492808/Downstream/1231;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/16373, chr1-CpG: 38/Downstream/9550
Upstream sequence
ttcagaGGGCCCAAAAGCAGGGGTGTGCCCCAGCCCCAGACACCTCCCTGGCTCTTTAAAGTCTGGGCCAGTCCTGGGTAGGGAAATGCAGGGCAGGGTC
Downstream sequence
CCTGGGTGGGATGTGACGAGGAGAGGCCCAGAGAGGTGGGCTCGGACCCAGCTCCTGAGGAACATGCCGTGAAGAGCTGGGGACTGCTGGCTGCCCGCAT
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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