Basic Information
VIS ID
TVIS30000405
Fusion event
HIV-EPS15 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr1
Cytoband
p32.3
Reference genome
GRCh37/hg19
Start
51960821/51495149 (Hg38)
End
51960821/51495149 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1B
Target gene
EPS15
miRNAs that regulate target gene
hsa-mir-374a-5p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-181d-5p ; hsa-mir-181b-5p ; hsa-mir-181c-5p ; hsa-mir-181a-5p
Nearest miRNA
hsa-mir-12136/Upstream/435046; hsa-mir-101-1/Downstream/341195;
Nearest TSS
ENST00000473358/Upstream/29823; ENST00000415031/Downstream/23160;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/150134, chr1-CpG: 66/Downstream/23556
Upstream sequence
GGTCCACTGGACTTGTAATTATAAagtatgcaagcctgaagctttataatcatcttagttctacaacagaataatttgccttagaatggagccaaggtac
Downstream sequence
aaaaaaagaaaaactaagtagtgacatcactgtgaccctgacacaccagaagccaggtctactaatggacctaccatttatataaactaatgttttctgc
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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