Basic Information
VIS ID
TVIS30000411
Fusion event
HIV-CDC14A integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr1
Cytoband
p21.2
Reference genome
GRCh37/hg19
Start
100886731/100421175 (Hg38)
End
100886731/100421175 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1E
Target gene
CDC14A
miRNAs that regulate target gene
hsa-mir-503-5p ; hsa-mir-424-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-628-3p ; hsa-mir-630 ; hsa-mir-301a-3p
Nearest miRNA
hsa-mir-101-1/Upstream/139867; hsa-mir-11399/Downstream/7476048;
Nearest TSS
ENST00000473358/Upstream/58014; ENST00000469387/Downstream/2557;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/67832, chr1-CpG: 146/Downstream/117837
Upstream sequence
ATGTACCACCCACTAAAATGATGTGGTACACCAAACATTATCTGTGCAAATGCTTTTGTTAAGTTGTATTAGTCAAAAGTTTGGGGAAAGTTCTGGTTTG
Downstream sequence
GGTTTATATATGTTAATACCTAGCGAGAAAAGTAGACAGCATATTCTTTCTTTCCCCTTAGGAGCACAAGAGAAAAAATCAAGATATTTAGAAGATGCTT
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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