Basic Information
VIS ID
TVIS30000414
Fusion event
HIV-VPS45 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr1
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
150073817/150101711 (Hg38)
End
150073817/150101711 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1F
Target gene
VPS45
miRNAs that regulate target gene
hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-34a-5p ; hsa-mir-186-5p ; hsa-mir-100-5p ; hsa-mir-99a-5p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-5695 ; hsa-mir-519d-5p ; hsa-mir-186-3p ; hsa-mir-6782-3p ; hsa-mir-4429 ; hsa-mir-320d ; hsa-mir-320c ; hsa-mir-320b ; hsa-mir-320a
Nearest miRNA
hsa-mir-101-1/Upstream/1713348; hsa-mir-1182/Downstream/390634;
Nearest TSS
ENST00000473358/Upstream/9706; ENST00000618148/Downstream/7464;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/33953, chr1-CpG: 190/Downstream/47794
Upstream sequence
taatctcagctactcgggaggcagaggcaggagaatggcttgaacccgggaggcaaaggttgcagtgagctgagatcgcatcattgcactccagctctgg
Downstream sequence
gcgacagagcaagactccaccttgaaaaaaaaaaaaagtcaaaaataacagaacctggcgaggctgcagagaaaagggaacacttgtatgctgttggtgg
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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